2025 rs660 is a single nucleotide polymorphism (SNP) located on chromosome 1 in the human genome. SNPs are variations in a single nucleotide that occur at a specific position in the DNA sequence. The 2025 rs660 SNP involves a change from a cytosine (C) to a thymine (T) nucleotide at position 2025 in the gene encoding the enzyme methylenetetrahydrofolate reductase (MTHFR).
The MTHFR enzyme plays a crucial role in the metabolism of folate, a B vitamin that is essential for various bodily functions, including DNA synthesis, cell growth, and amino acid metabolism. The 2025 rs660 SNP can result in decreased MTHFR enzyme activity, which can lead to reduced folate levels and an increased risk of certain health conditions, such as neural tube defects in newborns and cardiovascular disease in adults.
